重组人ARMET/ARP蛋白(ab201386)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, HPLC, Functional Studies
描述
-
产品名称
重组人ARMET/ARP蛋白
参阅全部 ARMET/ARP 蛋白酶 -
生物活性
Fully biologically active when compared to standard.
The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 20 μg/ml, corresponding to a specific activity of > 50 IU/mg.
-
纯度
> 95 % SDS-PAGE.
> 95 % by HPLC. -
表达系统
Escherichia coli -
Accession
-
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
序列
LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL -
预测分子量
18 kDa -
氨基酸
25 to 182 -
额外的序列信息
A single non-glycosylated polypeptide chain containing 158 amino acids. This product is the mature full length protein without the signal peptide.
-
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab201386 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
HPLC
Functional Studies
-
形式
Lyophilized -
补充说明
This product was previously labelled as ARMET
-
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBSThis product is an active protein and may elicit a biological response in vivo, handle with caution.
-
复溶Briefly centrifuge prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
常规信息
-
别名
- Arginine rich mutated in early stage tumors
- Arginine rich protein
- Arginine-rich protein
see all -
功能
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. -
序列相似性
Belongs to the ARMET family. -
结构域
The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response. -
翻译后修饰
May contain sialic acid residues. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (0)
ab201386 尚未被引用在任何文献中。