Recombinant人ARMET protein (ab124557)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP55145
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMGSHMLRPGDCEVCISYLGRFYQDLKDRDV TFSPATIENELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHH IPVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLRVKELKKILDDWGE TCKGCAEKSDYIRKINELMPKYAPKAASARTDL
    • 分子量21 kDa including tags
    • 氨基酸25 to 182
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab124557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    Purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • Arginine rich mutated in early stage tumors
    • Arginine rich protein
    • Arginine-rich protein
    • ARMET
    • ARMET protein
    • ARP
    • Manf
    • MANF_HUMAN
    • Mesencephalic astrocyte derived neurotrophic factor
    • Mesencephalic astrocyte-derived neurotrophic factor
    • MGC142148
    • MGC142150
    • Protein ARMET
    see all
  • 功能Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
  • 序列相似性Belongs to the ARMET family.
  • 结构域The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
  • 翻译后修饰May contain sialic acid residues.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant Human ARMET protein 图像

  • 15% SDS-PAGE analysis of 3 µg of ARMET protein (ab124557).

Recombinant Human ARMET protein (ab124557)参考文献

ab124557 has not yet been referenced specifically in any publications.

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