重组人Arg2蛋白(ab97349)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, MS
描述
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产品名称
重组人Arg2蛋白
参阅全部 Arg2 蛋白酶 -
纯度
> 95 % SDS-PAGE.
ab97349 is purified using conventional chromatography techniques. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MGSSHHHHHHSSGLVPRGSHMVHSVAVIGAPFSQGQKRKGVEHGPAAIRE AGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAE VVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTP LTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISASIVYIGLRDVD PPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDI DAFDPTLAPATFTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLA TSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARV RI -
预测分子量
38 kDa including tags -
氨基酸
23 to 354 -
标签
His tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab97349 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Mass Spectrometry
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质谱法
MALDI-TOF-TOF -
形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00
Constituents: 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine)
常规信息
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别名
- ARG2
- ARGI2_HUMAN
- Arginase II mitochondrial
see all -
功能
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. -
组织特异性
Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas. -
通路
Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1. -
序列相似性
Belongs to the arginase family. -
细胞定位
Mitochondrion. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab97349 被引用在 1 文献中.
- Guo X et al. Rational design of novel irreversible inhibitors for human arginase. Bioorg Med Chem 26:3939-3946 (2018). PubMed: 29914772