Recombinant人APRT protein (ab116469)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP07741
    • 种属Human
    • 序列MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHL KATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWAS YSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEV LECVSLVELTSLKGREKLAPVPFFSLLQYE
    • 分子量20 kDa including tags
    • 氨基酸1 to 180

技术指标

Our Abpromise guarantee covers the use of ab116469 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab116469 is purified by proprietary chromatographic techniques.
  • 形式Liquid
  • 补充说明Although stable 4°C for 4 weeks, ab116469 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 10% Glycerol

常规信息

  • 别名
    • Adenine phosphoribosyltransferase
    • AMP
    • AMP diphosphorylase
    • AMP pyrophosphorylase
    • APRT
    • APT_HUMAN
    • DKFZp686D13177
    • MGC125856
    • MGC125857
    • MGC129961
    • Transphosphoribosidase
    see all
  • 功能Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  • 通路Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.
  • 疾病相关Defects in APRT are the cause of adenine phosphoribosyltransferase deficiency (APRTD) [MIM:102600]; also known as 2,8-dihydroxyadenine urolithiasis. An enzymatic deficiency that can lead to urolithiasis and renal failure. Patients have 2,8-dihydroxyadenine (DHA) urinary stones.
  • 序列相似性Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human APRT protein (ab116469)参考文献

ab116469 has not yet been referenced specifically in any publications.

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