Recombinant人APAF1 protein (ab112251)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionO14727
    • 种属Human
    • 序列GEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGY IKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE
    • 分子量37 kDa including tags
    • 氨基酸1138 to 1237
    • 标签GST tag N-Terminus

相关产品

技术指标

Our Abpromise guarantee covers the use of ab112251 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式Liquid
  • 补充说明Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别���
    • APAF 1
    • Apaf-1
    • APAF_HUMAN
    • Apaf1
    • Apoptotic peptidase activating factor 1
    • Apoptotic protease activating factor
    • Apoptotic protease activating factor 1
    • Apoptotic protease-activating factor 1
    • CED 4
    • CED4
    • KIAA0413
    see all
  • 功能Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
  • 组织特异性Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.
  • 序列相似性Contains 1 CARD domain.
    Contains 1 NB-ARC domain.
    Contains 13 WD repeats.
  • 结构域The CARD domain mediates interaction with APIP.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human APAF1 protein 图像

  • Coomassie Blue stained 12.5% SDS page analysis of ab112251

Recombinant Human APAF1 protein (ab112251)参考文献

ab112251 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab112251.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"