Recombinant人Anterior Gradient 2 protein (ab64013)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSM RDT TVKPGAKKDT KDSRPKLPQT LSRGWGDQLI WTQTYEEALY KSKTSNKPLM IIHHLDECPH SQALKKVFAE NKEIQKLAEQ FVLLNLVYET TDKHLSPDGQ YVPRIMFVDP SLTVRADITG RYSNRLYAYE PADTALLLDN MKKALKLLKT EL
    • 氨基酸
      21 to 175

技术指标

Our Abpromise guarantee covers the use of ab64013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS, pH 7.4

常规信息

  • 别名
    • AG 2
    • AG 2 protein
    • AG-2
    • AG2
    • AG2 protein
    • AGR 2
    • AGR2
    • AGR2_HUMAN
    • anterior gradient 2 homolog
    • Anterior gradient 2 homolog (Xenopus laevis)
    • Anterior gradient 2, protein disulphide isomerase family member
    • Anterior gradient 2, Xenopus, homolog of
    • Anterior gradient homolog 2
    • Anterior gradient protein 2 homolog
    • Epididymis secretory protein Li 116
    • GOB 4
    • GOB4
    • HAG 2
    • hAG-2
    • hAG2
    • HAG2/R
    • HEL S 116
    • HPC 8
    • hPC8
    • PDIA17
    • Protein disulfide isomerase family A member 17
    • secreted cement gland homolog
    • Secreted cement gland protein XAG 2 homolog
    • Secreted cement gland protein XAG-2 homolog
    • Secreted cement gland protein XAG2 homolog
    • XAG 2
    • XAG2
    see all
  • 功能
    Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
  • 组织特异性
    Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.
  • 序列相似性
    Belongs to the AGR family.
  • 细胞定位
    Secreted. Endoplasmic reticulum.
  • Information by UniProt

图片

  • SDS page analysis of ab64013

文献

This product has been referenced in:
  • Arumugam T  et al. New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice. Mol Cancer Ther 14:941-51 (2015). Read more (PubMed: 25646014) »

See 1 Publication for this product

客户评价及客户问答

Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products. I am sorry this peptide wasshorter than stated on the datasheet and for the inconvenience this has caused. A...

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The endotoxin level is above 1.0 EU per 1 ug of protein by LAL method. Exact endotoxin level is unknown.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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