Recombinant人Annexin A1 protein (ab88803)

概述

描述

  • 性质Recombinant
  • 来源Saccharomyces cerevisiae
  • 氨基酸序列
    • 种属Human
    • 序列MAMVSEFLKQ AWFIENEEQE YVQTVKSSKG GPGSAVSPYP TFNPSSDVAA LHKAIMVKGV DEATIIDILT KRNNAQRQQI KAAYLQETGK PLDETLKKAL TGHLEEVVLA LLKTPAQFDA DELRAAMKGL GTDEDTLIEI LASRTNKEIR DINRVYREEL KRDLAKDITS DTSGDFRNAL LSLAKGDRSE DFGVNEDLAD
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab88803 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab88803 was purified by affinity Chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5

常规信息

  • 别名
    • Annexin 1
    • Annexin A1
    • Annexin I
    • Annexin I (lipocortin I)
    • Annexin-1
    • AnnexinA1
    • AnnexinI
    • ANX 1
    • ANX A1
    • ANX1
    • ANXA 1
    • ANXA1
    • ANXA1 protein
    • ANXA1_HUMAN
    • Calpactin 2
    • Calpactin II
    • Calpactin-2
    • CalpactinII
    • Chromobindin 9
    • Chromobindin-9
    • Chromobindin9
    • HGNC:533
    • Lipocortin 1
    • Lipocortin I
    • Lipocortin1
    • LipocortinI
    • LPC 1
    • LPC1
    • p35
    • Phospholipase A2 inhibitory protein
    see all
  • 功能Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
  • 序列相似性Belongs to the annexin family.
    Contains 4 annexin repeats.
  • 结构域A pair of annexin repeats may form one binding site for calcium and phospholipid.
  • 翻译后修饰Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.
  • 细胞定位Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages.
  • Information by UniProt

Recombinant Human Annexin A1 protein (ab88803)参考文献

This product has been referenced in:
  • Behrouz GF  et al. Presence of auto-antibody against two placental proteins, annexin A1 and vitamin D binding protein, in sera of women with pre-eclampsia. J Reprod Immunol 99:10-6 (2013). WB . Read more (PubMed: 23830177) »

See 1 Publication for this product

Product Wall

the tag is on the N-terminal part of the Annexin A1 protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"