重组人Angiotensin II Type 1 Receptor蛋白(ab157870)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: ELISA, WB
描述
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产品名称
重组人Angiotensin II Type 1 Receptor蛋白
参阅全部 Angiotensin II Type 1 Receptor 蛋白酶 -
表达系统
Wheat germ -
蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
FFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNP LFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRHSDNVSSST KKPAPCFEVE -
氨基酸
250 to 359 -
标签
GST tag N-Terminus
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技术指标
Our Abpromise guarantee covers the use of ab157870 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
ELISA
Western blot
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- AG2S
- Agtr 1
- Agtr1
see all -
功能
Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. -
组织特异性
Liver, lung, adrenal and adrenocortical adenomas. -
疾病相关
Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype). -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
翻译后修饰
C-terminal Ser or Thr residues may be phosphorylated. -
细胞定位
Cell membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (1)
ab157870 被引用在 1 文献中.
- Ferrão FM et al. Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells. Am J Physiol Renal Physiol 313:F440-F449 (2017). PubMed: 28468964