Recombinant人Aminoacylase 1 protein (ab99247)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ03154
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMTSKGPEEEHPSVTLFRQYLRIRTVQPKPD YGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSH TDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKV EGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFR EKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYNVIPATMSASFDFRVAPD VDFKAFEEQLQSWCQAAGEGVTLEFAQKWMHPQVTPTDDSNPWWAAFSRV CKDMNLTLEPEIMPAATDNRYIRAVGVPALGFSPMNRTPVLLHDHDERLH EAVFLRGVDIYTRLLPALASVPALPSDS
    • 分子量48 kDa including tags
    • 氨基酸1 to 408
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab99247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab99247 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • ACY 1
    • ACY-1
    • Acy1
    • ACY1_HUMAN
    • ACY1D
    • ACYLASE
    • Acylase I
    • Aminoacylase-1
    • EC 3.5.1.14
    • epididymis secretory protein Li 5
    • HEL-S-5
    • N acyl L amino acid amidohydrolase
    • N-acyl-L-amino-acid amidohydrolase
    • OTTHUMP00000212459
    • OTTHUMP00000212462
    • OTTHUMP00000212463
    • OTTHUMP00000212464
    • OTTHUMP00000212465
    see all
  • 功能Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).
  • 组织特异性Expression is highest in kidney, strong in brain and weaker in placenta and spleen.
  • 疾病相关Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D) [MIM:609924]. ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids.
  • 序列相似性Belongs to the peptidase M20A family.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human Aminoacylase 1 protein 图像

  • 15% SDS-PAGE showing ab99247 (3µg).

Recombinant Human Aminoacylase 1 protein (ab99247)参考文献

ab99247 has not yet been referenced specifically in any publications.

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