Recombinant人Amino-terminal enhancer of split protein (ab104756)

概述

  • 产品名称
    Recombinant人Amino-terminal enhancer of split protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMMFPQSRHSGSSHLPQQLKFTTSDSCDRIK DEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAE IVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQQLQAH QLSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSLSALGSQAHLSKEDK NGHDGDTHQEDDGEKSD
    • 分子量
      24 kDa including tags
    • 氨基酸
      1 to 197
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab104756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 95 % SDS-PAGE.
    ab104756 is purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • aes
    • Aes 1
    • Aes 2
    • AES_HUMAN
    • Aes1
    • Aes2
    • Amino enhancer of split
    • Amino terminal enhancer of split
    • Amino-terminal enhancer of split
    • Esp 1
    • Esp1
    • Gp130 associated protein GAM
    • Gp130-associated protein GAM
    • GRG
    • GRG 5
    • GRG protein
    • Grg-5
    • GRG5
    • Groucho-related protein 5
    • Protein ESP 1
    • Protein ESP1
    • Protein GRG
    • TLE 5
    • TLE5
    see all
  • 功能
    Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.
  • 组织特异性
    Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver.
  • 序列相似性
    Belongs to the WD repeat Groucho/TLE family.
  • 结构域
    Lacks the C-terminal WD repeats.
  • 翻译后修饰
    Ubiquitinated by XIAP/BIRC4.
  • 细胞定位
    Nucleus.
  • Information by UniProt

图片

  • 15% SDS-PAGE (3µg).

文献

ab104756 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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