Recombinant人ALR protein (ab114811)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP55789-2
    • 种属Human
    • 序列MRTQQKRDTKFREDCPPDREELGRHSWAVLHTLAAYYPDLPTPEQQQDMA QFIHLFSKFYPCEECAEDLRKRLCRNHPDTRTRACFTQWLCHLHNEVNRK LGKPDFDCSKVDERWRDGWKDGSCD
    • 分子量40 kDa including tags
    • 氨基酸1 to 125

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技术指标

Our Abpromise guarantee covers the use of ab114811 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • ALR_HUMAN
    • Augmenter of liver regeneration
    • ERV1
    • ERV1 homolog
    • Erv1 like growth factor
    • FAD-linked sulfhydryl oxidase ALR
    • GFER
    • Growth factor augmenter of liver regeneration
    • Growth factor erv1 like
    • Hepatic regenerative stimulation substance
    • Hepatopoietin
    • Hepatopoietin protein
    • hERV1
    • HPO
    • HPO1
    • HPO2
    • HSS
    see all
  • 功能Isoform 1: FAD-dependent sulfhydryl oxidase. Within the mitochondrial intermembrane space, participates in a chain of disulfide exchange reactions with MIA40, that generate disulfide bonds in a number of resident proteins with twin Cx3C and Cx9C motifs.
    Isoform 2: May act as an autocrine hepatotrophic growth factor promoting liver regeneration.
  • 组织特异性Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle.
  • 疾病相关Defects in GFER are a cause of mitochondrial progressive myopathy with congenital cataract hearing loss and developmental delay (MPMCHD) [MIM:613076]; also called combined mitochondrial complex deficiency.
  • 序列相似性Contains 1 ERV/ALR sulfhydryl oxidase domain.
  • 细胞定位Mitochondrion intermembrane space and Cytoplasm. Secreted.
  • Information by UniProt

Recombinant Human ALR protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

Recombinant Human ALR protein (ab114811)参考文献

ab114811 has not yet been referenced specifically in any publications.

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