Recombinant人alpha smooth muscle Actin protein (ab114148)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP62736
    • 种属Human
    • 序列MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMG QKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAP EEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRT TGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGY SFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVI TIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNV LSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILAS LSTFQQMWISKQEYDEAGPSIVHRKCF
    • 分子量67 kDa including tags
    • 氨基酸1 to 377
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab114148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • a actin
    • AAT6
    • ACTA_HUMAN
    • ACTA2
    • Actin alpha 2 smooth muscle aorta
    • Actin aortic smooth muscle
    • Actin, aortic smooth muscle
    • ACTSA
    • ACTVS
    • Alpha 2 actin
    • Alpha actin 2
    • Alpha cardiac actin
    • Alpha-actin-2
    • Cell growth inhibiting gene 46 protein
    • Cell growth-inhibiting gene 46 protein
    • GIG46
    • Growth inhibiting gene 46
    • MYMY5
    see all
  • 功能Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
  • 疾病相关Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
  • 序列相似性Belongs to the actin family.
  • 细胞定位Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human alpha smooth muscle Actin protein 图像

  • 12.5% SDS-PAGE analysis of ab114148, stained with Coomassie Blue.

Recombinant Human alpha smooth muscle Actin protein (ab114148)参考文献

ab114148 has not yet been referenced specifically in any publications.

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