Recombinant人alpha 1 Glycine Receptor protein (ab114750)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP23415
    • 种属Human
    • 序列IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDL KNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEE
    • 分子量37 kDa including tags
    • 氨基酸121 to 220

技术指标

Our Abpromise guarantee covers the use of ab114750 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备���贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • GLRA1
    • GLRA1_HUMAN
    • Glycine receptor 48 kDa subunit
    • Glycine receptor alpha 1
    • Glycine receptor strychnine-binding subunit
    • Glycine receptor subunit alpha-1
    • Glycine receptor, alpha 1 subunit
    • HKPX1
    • STHE
    see all
  • 功能The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
  • 疾病相关Defects in GLRA1 are a cause of startle disease (STHE) [MIM:149400]; also known as hereditary hyperekplexia or congenital stiff-person syndrome. STHE is a genetically heterogeneous neurologic disorder characterized by muscular rigidity of central nervous system origin, particularly in the neonatal period, and by an exaggerated startle response to unexpected acoustic or tactile stimuli. Inheritance can be autosomal dominant or recessive.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt

Recombinant Human alpha 1 Glycine Receptor protein 图像

  • 12.5% SDS-PAGE Stained with Coomassie Blue showing ab114750 at approximately 36.63kDa.

Recombinant Human alpha 1 Glycine Receptor protein (ab114750)参考文献

ab114750 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114750.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"