Recombinant人alpha 1 Fetoprotein (ab114216)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP02771
    • 种属Human
    • 序列MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIF FAQFVQEATYKEVSKMVKDALTAIE KPTGDEQSSGCLENQLPAFLEEL CHEKEILEKYGHSDCCSQSEEGRHNCFLAHKKPTPASIPLFQVPEPVTSC EA YEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDKIIPSCCKAE NAVECFQTKAATVTKELRESSLLNQHACA VMKNFGTRTFQAITVTKLS QKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDT LSNKIT ECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQF SSGEKNIFLASFVHEYSRRHPQLAVSVILRVAK GYQELLEKCFQTENP LECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAP QLTSSELMAI TRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRH EMTPVNTGVGQCCTSSYANRRPCFSSLVVDETYVPPA FSDDKFIFHKD LCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQ EQEVCFAEEGQKLI SKTRAALGV
    • 分子量93 kDa including tags
    • 氨基酸1 to 609

技术指标

Our Abpromise guarantee covers the use of ab114216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Best use within three months from the date of receipt of this protein.
    Protein concentration is lot specific and is above or equal to 0.05 mg/ml
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Afp
    • Alpha fetoglobulin
    • Alpha fetoprotein
    • Alpha fetoprotein precursor
    • Alpha-1-fetoprotein
    • Alpha-fetoglobulin
    • Alpha-fetoprotein
    • alpha-fetoprotein, Hereditary persistence of, included
    • FETA
    • FETA_HUMAN
    • Hereditary persistence of alpha fetoprotein
    • HPAFP
    see all
  • 功能Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
  • 组织特异性Plasma. Synthesized by the fetal liver and yolk sac.
  • 序列相似性Belongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.
  • 发展阶段Occurs in the plasma of fetuses more than 4 weeks old, reaches the highest levels during the 12th-16th week of gestation, and drops to trace amounts after birth. The serum level in adults is usually less than 40 ng/ml. AFP occurs also at high levels in the plasma and ascitic fluid of adults with hepatoma.
  • 翻译后修饰Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.
    Sulfated.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant Human alpha 1 Fetoprotein 图像

  • ab114216 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Recombinant Human alpha 1 Fetoprotein (ab114216)参考文献

This product has been referenced in:
  • Zhang A  et al. A Chemiluminescent Protein Microarray Method for Determining the Seroglycoid Fucosylation Index. Sci Rep 6:31132 (2016). Read more (PubMed: 27528397) »

See 1 Publication for this product

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The purity of ab114216 varies from batch to batch.

Generally, the purity is above 80%.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"