Recombinant人ALKBH3 protein (ab124851)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ96Q83
    • 种属Human
    • 序列MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELDM EEKRRRARVQ GAWAAPVKSQ AIAQPATTAK SHLHQKPGQT WKNKEHHLSD REFVFKEPQQ VVRRAPEPRV IDREGVYEIS LSPTGVSRVC LYPGFVDVKE ADWILEQLCQ DVPWKQRTGI REDITYQQPR LTAWYGELPY TYSRITMEPN PHWHPVLRTL KNRIEENTGH TFNSLLCNLY RNEKDSVDWH SDDEPSLGRC PIIASLSFGA TRTFEMRKKP PPEENGDYTY VERVKIPLDH GTLLIMEGAT QADWQHRVPK EYHSREPRVN LTFRTVYPDP RGAPW
    • 分子量38 kDa including tags
    • 氨基酸1 to 286
    • 标签His tag N-Terminus
    • 额外的序列信息ALKBH3 Human Recombinant fused to 39 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 325 amino acids (1-286 a.a.).

技术指标

Our Abpromise guarantee covers the use of ab124851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab124851 is purified by proprietary chromatographic techniques and sterile filtered.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • 1700108H04Rik
    • 1810020C19Rik
    • ABH3
    • AlkB homolog 3
    • alkB, alkylation repair homolog 3 (E. coli)
    • ALKB3_HUMAN
    • ALKBH3
    • Alkylated DNA repair protein alkB homolog 3
    • alkylation repair homolog 3
    • Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3
    • DEPC 1
    • DEPC-1
    • DEPC1
    • EC 1.14.11.
    • FLJ43614
    • mABH3
    • MGC118790
    • MGC118792
    • MGC118793
    • MGC134125
    • PCA1
    • Prostate cancer antigen 1
    • Prostate cancer antigen-1
    • RP23-375N21.4
    see all
  • 功能Dioxygenase that repairs alkylated DNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Has a strong preference for single-stranded DNA. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
  • 组织特异性Ubiquitous. Detected in heart, pancreas, skeletal muscle, thymus, testis, ovary, spleen, prostate, small intestine, peripheral blood leukocytes, urinary bladder and colon.
  • 序列相似性Belongs to the alkB family.
    Contains 1 Fe2OG dioxygenase domain.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt

Recombinant Human ALKBH3 protein (ab124851)参考文献

ab124851 has not yet been referenced specifically in any publications.

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