Recombinant人AKR7A3 protein (ab116489)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO95154
    • 种属Human
    • 序列MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELEM SRQLSRARPA TVLGAMEMGR RMDAPTSAAV TRAFLERGHT EIDTAFVYSE GQSETILGGL GLRLGGSDCR VKIDTKAIPL FGNSLKPDSL RFQLETSLKR LQCPRVDLFY LHMPDHSTPV EETLRACHQL HQEGKFVELG LSNYAAWEVA EICTLCKSNG WILPTVYQGM YNAITRQVET ELFPCLRHFG LRFYAFNPLA GGLLTGKYKY EDKDGKQPVG RFFGNTWAEM YRNRYWKEHH FEGIALVEKA LQAAYGASAP SMTSATLRWM YHHSQLQGAH GDAVILGMSS LEQLEQNLAA AEEGPLEPAV VDAFNQAWHL VAHECPNYFR
    • 分子量42 kDa including tags
    • 氨基酸1 to 331
    • 额外的序列信息AKR7A3 Human Recombinant fused to 39 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 370 amino acids (1-331 a.a.).

技术指标

Our Abpromise guarantee covers the use of ab116489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity: approximately < 0.1 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme catalyzing the oxidation of 1 micromole NADPH per minute at 25C. Specific activity was expressed as units/mg protein.
  • 应用

    SDS-PAGE

    Functional Studies

  • 纯度> 95 % SDS-PAGE.
    ab116489 was purified by proprietary chromatographic techniques and filter sterilized.
  • 形式Liquid
  • 补充说明 although stable at 4°C for 30 days, should be stored desiccated below -20°C for periods greater than 30 days. Please avoid freeze-thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 10% Glycerol

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • AFAR 2
    • AFAR2
    • AFB1 aldehyde reductase 2
    • AFB1 AR 2
    • AFB1-AR 2
    • Aflatoxin aldehyde reductase
    • Aflatoxin B1 aldehyde reductase 2
    • Aflatoxin B1 aldehyde reductase member 3
    • Akr7a3
    • Aldo keto reductase family 7 member A3
    • ARK73_HUMAN
    • OTTHUMP00000002623
    see all
  • 功能Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
  • 组织特异性Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
  • 序列相似性Belongs to the aldo/keto reductase 2 family.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant human AKR7A3 protein (ab116489)参考文献

ab116489 has not yet been referenced specifically in any publications.

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