Recombinant人AKR1D1 protein (ab104758)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMDLSAASHRIPLSDGNSIPIIGLGTYSEPK STPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRRE DIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELIL NKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIW VNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERI KENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY
    • 分子量
      40 kDa including tags
    • 氨基酸
      1 to 326
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab104758 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    ab104758 is purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, 1mM DTT, pH 8.0

常规信息

  • 别名
    • 3-oxo-5-beta-steroid 4-dehydrogenase
    • 3o5bred
    • AK1D1_HUMAN
    • AKR1D1
    • Aldo keto reductase family 1 member D1
    • aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase)
    • Aldo-keto reductase family 1 member D1
    • CBAS2
    • Delta(4) 3 ketosteroid 5 beta reductase
    • Delta(4) 3 oxosteroid 5 beta reductase
    • Delta(4)-3-ketosteroid 5-beta-reductase
    • Delta(4)-3-oxosteroid 5-beta-reductase
    • SRD5B1
    • steroid 5 beta reductase
    • steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1)
    see all
  • 功能
    Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
  • 组织特异性
    Highly expressed in liver. Expressed in testis and weakly in colon.
  • 疾病相关
    Congenital bile acid synthesis defect 2
  • 序列相似性
    Belongs to the aldo/keto reductase family.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • 15% SDS-PAGE (3µg).

文献

ab104758 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab104758.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册