Recombinant人ADRB1 Arg 389 + GsaL fusion protein (ab90775)

概述

  • 产品名称Recombinant人ADRB1 Arg 389 + GsaL fusion protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human
    • 额外的序列信息Tagged at the N terminus of the ADRB1 with a DDDDK tag. The C terminus of the ADRB1 is linked to the N terminus of the Gs alpha L with a His tag.

技术指标

Our Abpromise guarantee covers the use of ab90775 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

常规信息

  • 别名
    • Adenylate cyclase stimulating G alpha protein
    • ADRB1
    • ADRB1R
    • Adrenergic beta1 receptor
    • AHO
    • B1AR
    • Beta 1 adrenergic receptor
    • Beta 1 adrenoreceptor
    • BETA1AR
    • C20orf45
    • GNAS
    • GNAS complex locus
    • GNAS1
    • GPSA
    • GSA
    • GSP
    • Guanine nucleotide binding protein (G protein) alpha stimulating activity polypeptide 1
    • Guanine nucleotide binding protein G(s) subunit alpha isoforms short
    • Guanine nucleotide regulatory protein
    • MGC33735
    • PHP1A
    • PHP1B
    • POH
    • RHR
    see all
  • 相关性ADRB1 belongs to a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 have been shown to affect the resting heart rate and can be involved in heart failure. GsaL is the long splice variant of the alpha-subunit of the heterotrimeric G-protein Gs. Gs activates the effector adenylate cyclase. GsaL differs from the short splice variant by a 15 amino acid insert between the ras-like domain and the alpha-helical domain.
  • 细胞定位ADRB1: Cell membrane; Multi-pass membrane protein. Note: Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression.

Recombinant Human ADRB1 Arg 389 + GsaL fusion protein (ab90775)参考文献

ab90775 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"