Recombinant人ADBR2 + Gia2 fusion protein (ab90752)

概述

  • 产品名称Recombinant人ADBR2 + Gia2 fusion protein
  • 蛋白长度Full length protein
  • 描述
    Recombinant人ADBR2 + Giα2 fusion protein

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human
    • 分子量90 kDa
    • 额外的序列信息Tagged at the N terminus of the ADBR2 with a DDDDK tag. The C terminus of the ADBR2 is linked to the N terminus of the Gi alpha 2 with a His tag.

技术指标

Our Abpromise guarantee covers the use of ab90752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Activity: 4-15 pmol/mg.
  • 应用

    Functional Studies

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Adenylate cyclase inhibiting G alpha protein
    • ADRB2
    • ADRB2R
    • ADRBR
    • Adrenergic beta 2 receptor surf
    • B2AR
    • BAR
    • beta 2 adrenoceptor
    • Beta 2 adrenoreceptor
    • BETA2AR
    • Catecholamine receptor
    • GIP
    • GNAI 2
    • GNAI2B
    • GTP binding regulatory protein Gi alpha 2 chain
    • Guanine nucleotide binding protein G protein alpha inhibiting activity polypeptide 2
    • H LUCA15.1
    • H LUCA16.1
    • WUGSC:H LUCA15.1
    • WUGSC:H LUCA16.1
    see all
  • 相关性ADBR2 is a member of the G protein-coupled receptor superfamily. It is activated by the catecholamine epinephrine and couples to the G protein Gs to mediate adenylate cyclase activation. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. The G protein family of signal transducers includes 5 heterotrimers, which are most clearly distinguished by their different alpha chains; they have virtually identical beta chains and similar gamma chains. G protein alpha inhibitor chain 2 is a subunit of the G(i) G protein, whose role is in inhibiting adenylate cyclase activity in response to bound GTP. The G proteins possess GTPase activity and are components of a complex membrane signaling system that includes membrane bound receptors. The system exists to modulate extracellular signals as they are transmitted into the cell.
  • 细胞定位ADBR2: Cell Membrane

Recombinant human ADBR2 + Gia2 fusion protein (ab90752)参考文献

ab90752 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab90752.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"