重组人ADAM2蛋白(ab117063)
Key features and details
- Expression system: Wheat germ
- Suitable for: WB, SDS-PAGE, ELISA
描述
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产品名称
重组人ADAM2蛋白 -
表达系统
Wheat germ -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MWRVLFLLSGLGGLRMDSNFDSLPVQITVPEKIRSIIKEGIESQASYKIV IEGKPYTVNLMQKNFLPHNFRVYSYSGTGIMKPLDQDFQNFCHYQGYIEG YPKSVVMVSTCTGLRGVLQFENVSYGIEPLESSVGFEHVIYQVKHKKADV SLYNEKDIESRDLSFKLQSVEYNHMGSDTTVVAQKVFQLIGLTNAIFVSF NITIILSSLELWIDENKIATTGEANELLHTFLRWKTSYLVLRPHDVAFLL VYREKSNYVGATFQGKMCDANYAGGVVLHPRTISLESLAVILAQLLSLSM GITYDDINKCQCSGAVCIMNPEAIHFSGVKIFSNCSFEDFAHFISKQKSQ CLHNQPRLDPFFKQQAVCGNAKLEAGEECDCGTEQDCALIGETCCDIATC RFKAGSNCAEGPCCENCLFMSKERMCRPSFEECDLPEYCNGSSASCPENH YVQTGHPCGLNQWICIDGVCMSGDKQCTDTFGKEVEFGPSECYSHLNSKT DVSGNCGISDSGYTQCEADNLQCGKLICKYVGKFLLQIPRATIIYANISG HLCIAVEFASDHADSQKMWIKDGTSCGSNKVCRNQRCVSSSYLGYDCTTD KCNDRGVCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPAR LPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTE DYSSDEQPESESEPKG -
预测分子量
105 kDa including tags -
氨基酸
1 to 716
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技术指标
Our Abpromise guarantee covers the use of ab117063 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
SDS-PAGE
ELISA
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.3% Glutathione, 0.79% Tris HCl
常规信息
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别名
- A disintegrin and metalloproteinase domain 2
- ADAM 2
- ADAM metallopeptidase domain 2
see all -
功能
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein. -
组织特异性
Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues. -
序列相似性
Contains 1 disintegrin domain.
Contains 1 EGF-like domain.
Contains 1 peptidase M12B domain. -
结构域
A tripeptide motif (FEE) within disintegrin-like domain could be involved in the binding to egg integrin receptor and thus could mediate sperm/egg binding. -
翻译后修饰
The prodomain and the metalloprotease domain are cleaved during the epididymal maturation of the spermatozoa. -
细胞定位
Membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab117063 尚未被引用在任何文献中。