Recombinant人Activin A Receptor Type IB protein (ab55682)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human
    • 分子量57 kDa
    • 标签GST tag N-Terminus
    • 额外的序列信息Recombinant fragment corresponding to amino acids 150-end of Human Activin A Receptor Type IB.

相关产品

技术指标

Our Abpromise guarantee covers the use of ab55682 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab55682 purity was determined by densitometry.
  • 形式Liquid
  • 补充说明

    ab91090 (Cow Casein full length protein) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Activin A receptor type 1B
    • Activin A receptor type II like kinase 4
    • Activin A type 1B receptor
    • Activin A type IB receptor
    • Activin receptor like kinase 4
    • Activin receptor type 1B
    • Activin receptor type IB
    • Activin receptor type-1B
    • Activin receptor-like kinase 4
    • ACTR IB
    • ACTR-IB
    • ACTRIB
    • ACV1B_HUMAN
    • ACVR 1B
    • Acvr1b
    • ACVRLK 4
    • ACVRLK4
    • ALK 4
    • ALK-4
    • ALK4
    • Serine(threonine) protein kinase receptor R2
    • Serine/threonine-protein kinase receptor R2
    • SKR 2
    • SKR2
    see all
  • 功能On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TDP2.
  • 组织特异性Expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.
  • 序列相似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant human Activin A Receptor Type IB protein 图像

  • Sample Kinase Activity assay plot, using ab55682.
  • Sample purity data showing SDS-PAGE analysis of ab55682, with molecular weight markers.

Recombinant human Activin A Receptor Type IB protein (ab55682)参考文献

ab55682 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab55682.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"