Recombinant人Aconitase 1 protein (ab103501)

概述

  • 产品名称Recombinant人Aconitase 1 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP21399
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMGSMSNPFAHLAEPLDPVQPGKKFFNLNKL EDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIENILHWNVTQHKNIEVP FKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPADLVIDHS IQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGII HQVNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAE AVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKF VEFFGPGVAQLSIADRATIANMCPEYGATAAFFPVDEVSITYLVQTGRDE EKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVELDLKTVVPCCSGPKRPQ DKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNTEFTLAHG SVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGV VTYYLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLV AVGVLSGNRNFEGRVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGV NAKGQQVFLKDIWPTRDEIQAVERQYVIPGMFKEVYQKIETVNESWNALA TPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVDAYVLLNLGDSVTT DHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTFANI RLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAG SSRDWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADAL GLTGQERYTIIIPENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNG GILNYMIRKMAK
    • 分子量101 kDa including tags
    • 氨基酸1 to 889
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab103501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab103501 was purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, pH 8.0

常规信息

  • 别名
    • ACO 1
    • ACO1
    • ACOC_HUMAN
    • Aconitase
    • Aconitase 1 soluble
    • Aconitase1
    • Aconitate hydratase
    • ACONS
    • Citrate hydro lyase
    • Citrate hydro-lyase
    • Cytoplasmic aconitate hydratase
    • Ferritin repressor protein
    • IRE BP 1
    • IRE-BP 1
    • IREB 1
    • IREB1
    • IREBP
    • IREBP1
    • Iron regulatory protein 1
    • Iron responsive element binding protein 1
    • Iron-responsive element-binding protein 1
    • IRP 1
    • IRP1
    • OTTHUMP00000045233
    see all
  • 功能Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
    Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
  • 序列相似性Belongs to the aconitase/IPM isomerase family.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human Aconitase 1 protein 图像

  • 15% SDS-PAGE analysis of 3µg ab103501.

Recombinant Human Aconitase 1 protein (ab103501)参考文献

ab103501 has not yet been referenced specifically in any publications.

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