Recombinant人ABH2 protein (ab105622)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMDRFLVKGAQGGLLRKQEEQEPTGEEPAVL GGDKESTRKRPRREAPGNGGHSAGPSWRHIRAEGLDCSYTVLFGKAEADE IFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLS PKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP GSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPT NTHWYHSLPVRKKVLAPRVNLTFRKILLTKK
    • 分子量
      31 kDa including tags
    • 氨基酸
      1 to 261
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab105622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    ab105622 was purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 30% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • 2OG Fe(II) oxy DC1
    • 9530023G02
    • ABH 2
    • ABH2
    • alkB alkylation repair homolog 2
    • ALKB2_HUMAN
    • ALKBH2
    • ALKBH2 alkB
    • Alkylated DNA repair protein alkB homolog
    • Alkylated DNA repair protein alkB homolog 2
    • Alkylation repair homolog 2
    • Alpha ketoglutarate dependent dioxygenase alkB homolog 2
    • Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2
    • AU016977
    • DNA oxidative demethylase ALKBH2
    • EC 1.14.11.
    • FLJ99103
    • hABH2
    • mABH2
    • MGC90512
    • Oxy DC1
    see all
  • 功能
    Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
  • 组织特异性
    Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder.
  • 序列相似性
    Belongs to the alkB family.
    Contains 1 Fe2OG dioxygenase domain.
  • 细胞定位
    Nucleus. Detected in replication foci during S-phase.
  • Information by UniProt

图片

  • 15% SDS-PAGE analysis of ab105622 (3µg)

文献

ab105622 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your call today and letting us know about the trouble with ab105622.

As we discussed, I'd be happy to give you a 20% discount on another vial of ab105622 or alternatively you can participate in our testing discount program. In t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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