Recombinant人5 Lipoxygenase protein (ab114310)

概述

  • 产品名称
    Recombinant人5 Lipoxygenase protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGA VDSYDVTVDEELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPC YRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNP GFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQS SWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCT ELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLL AKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAH VRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLC FPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVV EEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQ HAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIA ERNKKKQLPYYYLSPDRIPNSVAI
    • 分子量
      100 kDa including tags
    • 氨基酸
      1 to 674

技术指标

Our Abpromise guarantee covers the use of ab114310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • 5 LO
    • 5 LOX
    • 5-lipoxygenase
    • 5-LO
    • 5-LOX
    • 5LOX
    • 5LPG
    • ALOX 5
    • Alox5
    • Arachidonate 5 lipoxygenase
    • Arachidonate 5-lipoxygenase
    • arachidonic 5-lipoxygenase alpha-10 isoform
    • arachidonic 5-lipoxygenase delta-10-13 isoform
    • arachidonic 5-lipoxygenase delta-13 isoform
    • arachidonic 5-lipoxygenase delta-p10 isoform
    • Arachidonic acid 5 lipoxygenase
    • Leukotriene A4 synthase
    • LOG 5
    • LOG5
    • LOX5_HUMAN
    • MGC163204
    see all
  • 功能
    Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.
  • 通路
    Lipid metabolism; leukotriene A4 biosynthesis.
  • 序列相似性
    Belongs to the lipoxygenase family.
    Contains 1 lipoxygenase domain.
    Contains 1 PLAT domain.
  • 翻译后修饰
    Serine phosphorylation by MAPKAPK2 is stimulated by arachidonic acid. Phosphorylation on Ser-523 by PKA has an inhibitory effect. Phosphorylation on Ser-272 prevents export from the nucleus.
  • 细胞定位
    Cytoplasm. Nucleus matrix. Nucleus membrane. Shuttles between cytoplasm and nucleus. Found exclusively in the nucleus, when phosphorylated on Ser-272. Calcium binding promotes translocation from the cytosol and the nuclear matrix to the nuclear envelope and membrane association.
  • Information by UniProt

Recombinant Human 5 Lipoxygenase protein 图像

  • SDS-PAGE analysis of ab114310 on a 12.5% gel stained with Coomassie Blue.

Recombinant Human 5 Lipoxygenase protein (ab114310)参考文献

ab114310 has not yet been referenced specifically in any publications.

Product Wall

Te pido disculpas por la espera.

He confirmado con mis compañeros del laboratorio que la proteína ab114310 puede también utilizarse como control positivo para el anticuerpo ab59341.

Si tuvieras cualquier otra co...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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