Recombinant人14-3-3 zeta protein (ab70258)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab70258 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5

常规信息

  • 别名
    • 14 3 3 delta
    • 14 3 3 protein zeta/delta
    • 14 3 3 protein/cytosolic phospholipase A2
    • 14 3 3 zeta
    • 14-3-3 protein zeta/delta
    • 1433Z_HUMAN
    • Epididymis luminal protein 4
    • Epididymis secretory protein Li 3
    • HEL S 3
    • HEL4
    • KCIP-1
    • KCIP1
    • MGC111427
    • MGC126532
    • MGC138156
    • Phospholipase A2
    • Protein kinase C inhibitor protein 1
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, delta polypeptide
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta polypeptide
    • Tyrosine 3/tryptophan 5 monooxygenase activation protein, zeta polypeptide
    • YWHAD
    • YWHAZ
    see all
  • 功能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
  • 序列相似性Belongs to the 14-3-3 family.
  • 翻译后修饰The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53. This phosphorylation appears to be activated by sphingosine. Phosphorylation on Thr-232; inhibits binding of RAF1.
  • 细胞定位Cytoplasm. Melanosome. Located to stage I to stage IV melanosomes.
  • Information by UniProt

Recombinant Human 14-3-3 zeta protein 图像

  • SDS PAGE showing Recombinant full-length human 14-3-3 zeta with N terminal tag at approximately 55kDa.

Recombinant Human 14-3-3 zeta protein (ab70258)参考文献

ab70258 has not yet been referenced specifically in any publications.

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