Recombinant HIV tat (mutated C31 A + C34 A) protein (ab119447)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列

技术指标

Our Abpromise guarantee covers the use of ab119447 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -80°C.

    Constituent: 0.1% Glycerol

  • 复溶ab119447 should be reconstituted in apirogenic sterile water or PBS buffer. Reconstituted protein should be used immediately.

常规信息

  • 别名
    • p14
    • Tat
    • Tat protein
    • Transactivating regulatory protein
  • 相关性The transcriptional transactivator (Tat) is a key regulatory protein of HIV. It is expressed early after the virus integrates into the cell, and stimulates the elongation of RNA polymerase II. It binds onto a sequence known as the TAR, or transactivator response element, located at the end of the HIV genetic chain. There, the tat protein helps assemble new copies of HIV. The tat protein-TAR complex speeds up the rate of viral reproduction by about a thousand times. If it is not present, the transcription process frequently stops short, and few functional HIV particles are produced. Tat is an important potential target for antiretrovirals and vaccine development.

Recombinant HIV tat (mutated C31 A + C34 A) protein (ab119447)参考文献

ab119447 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"