Recombinant HIV gp41 L protein (ab49071)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli

相关产品

技术指标

Our Abpromise guarantee covers the use of ab49071 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, 1.5M Urea, 25mM Tris HCl, 1mM EDTA

常规信息

  • 别名
    • env
    • Glycoprotein 41
    • gp41
    • TM
    • Transmembrane protein
    see all
  • 相关性The transmembrane protein gp41 (TM) acts as a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
  • 细胞定位Cell membrane

Recombinant HIV gp41 L protein (ab49071)参考文献

ab49071 has not yet been referenced specifically in any publications.

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