Recombinant丙型肝炎病毒genotype 6a NS5 protein (ab68377)

概述

  • 产品名称Recombinant丙型肝炎病毒genotype 6a NS5 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 氨基酸2212 to 2313
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab68377 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性ab68377 is immunoreactive with sera of HCV-infected individuals.
  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab68377 was purified by a proprietary chromatographic technique.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C.

    Preservative: None
    Constituents: 50% Glycerol, 0.2% Triton-X 1.5M Urea, 25mM Tris HCl, pH 8

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • HCV NS5
    • Hepatitis C virus non structural protein 5
    • Hepatitis C virus nonstructural protein 5
    • Hepatitis C Virus NS5
    • NS5A
    • p56
    see all
  • 相关性Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It's exact role is not currently known (2008). NS5B (non-structural protein 5B) is an RNA-dependant RNA polymerase responsible for replication of the hepatitis C viral genome, and is currently a principal target for chemotherapeutic inhibition of HCV replication.
  • 细胞定位Endoplasmic reticulum membrane

Recombinant Hepatitis C Virus genotype 6a NS5 protein (ab68377)参考文献

ab68377 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"