Recombinant Hepatitis A virus VP3 protein (ab68371)

概述

  • 产品名称Recombinant Hepatitis A virus VP3 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 分子量38 kDa
    • 氨基酸304 to 415

技术指标

Our Abpromise guarantee covers the use of ab68371 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性This protein is immunoreactive with sera from HAV-infected individuals.
  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    This protein was purified by proprietary chromatographic techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, 0.1% SDS, 10mM CBB, pH 9.6.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • HAV VP3
    • Hepatitis A VP3 protein
    • Virion protein 3
    • VP3
  • 相关性Hepatitis A Virus (HAV) is a 27nm nonenveloped, spherical, positive stranded RNA virus, classified within the genus hepatovirus of the picornavirus family and is among the smallest and structurally simplest of the RNA animal viruses. A single large polyprotein is expressed from a large open reading frame extending through most of the genomic RNA. This polyprotein is subsequently cleaved by a viral protease (3Cpro) to form three (possibly four) capsid proteins and several nonstructural proteins. HAV genomic replication occurs exclusively in the cytoplasm of the infected hepatocyte by a mechanism involving an RNA-dependent RNA polymerase. Though he clinical picture of viral (A) hepatitis is extremely variable - ranging from asymptotic infection without jaundice to a fulminating disease and death in a few days, Hepatitis A is usually a mild illness and does not lead to chronic or persistent hepatitis. HAV is transmitted by the orofecal route and is still endemic throughout much of the world, including the western world. HAV exists worldwide as a single serotype with a small degree of antigenetic variation. Present evidence suggests that immunity acquired naturally (or from an inactivated hepatitis A vaccine) will protect against all human HAV strains.
  • 细胞定位Cytoplasmic

Recombinant Hepatitis A virus VP3 protein (ab68371)参考文献

ab68371 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"