The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
内毒素水平< 0.100 Eu/µg
补充说明The ED50, determined by the dose-dependent stimulation of the proliferation of thymidine uptake by BaF3 cells expressing FGF receptors, is < 10.0 ng/ml, corresponding to a specific activity of > 1.0 x 105 units/mg.
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Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Acidic fibroblast growth factor
Beta endothelial cell growth factor
Beta-endothelial cell growth factor
Endothelial Cell Growth Factor alpha
Endothelial Cell Growth Factor beta
Fibroblast growth factor 1
Fibroblast Growth Factor 1 Acidic
Heparin binding growth factor 1
Heparin binding growth factor 1 precursor
Heparin-binding growth factor 1
功能The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.
序列相似性Belongs to the heparin-binding growth factors family.
细胞定位Secreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1.