Recombinant E. coli Nitroreductase protein (ab97948)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP38489
    • 种属Escherichia coli
    • 序列MGSSHHHHHHSSGLVPRGSHMDIISVALKRHSTKAFDASKKLTPEQAEQI KTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASH VVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHRK DLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV
    • 分子量26 kDa including tags
    • 氨基酸1 to 217
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab97948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 纯度> 95 % SDS-PAGE.
    ab97948 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • Dihydropteridine reductase
    • dprA
    • FMN dependent nitroreductase
    • nfnB
    • nfsI
    • ntr
    • Oxygen insensitive NAD(P)H nitroreductase
    see all
  • 相关性Nitroreductase shows the ability to reduce quinines. It is an enzyme for activating prodrugs in antibody directed enzyme prodrug therapy. It is also capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.

Recombinant E. coli Nitroreductase protein 图像

  • 15% SDS-PAGE showing ab97948 at approximately 26kDa (3µg).

Recombinant E. coli Nitroreductase protein (ab97948)参考文献

ab97948 has not yet been referenced specifically in any publications.

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