Recombinant E. coli Mannose Phosphate Isomerase protein (ab56727)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Escherichia coli

技术指标

Our Abpromise guarantee covers the use of ab56727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C.

    Constituent: 42.3% Ammonium sulphate

常规信息

  • 别名
    • PMI1
    • CDG1B
    • FLJ39201
    • Mannose 6 phosphate isomerase
    • Mannose-6-phosphate isomerase
    • MANNOSEPHOSPHATE ISOMERASE
    • MGC94106
    • MPI
    • MPI_HUMAN
    • Phosphohexomutase
    • Phosphomannose isomerase
    • phosphomannose isomerase 1
    • PMI
    see all
  • 功能Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
  • 组织特异性Expressed in all tissues, but more abundant in heart, brain and skeletal muscle.
  • 通路Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.
  • 疾病相关Defects in MPI are the cause of congenital disorder of glycosylation type 1B (CDG1B) [MIM:602579]; also known as carbohydrate-deficient glycoprotein syndrome type Ib (CDGS1B). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation. They are characterized by under-glycosylated serum glycoproteins. CDG1B is clinically characterized by protein-losing enteropathy.
  • 序列相似性Belongs to the mannose-6-phosphate isomerase type 1 family.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant E. coli Mannose Phosphate Isomerase protein (ab56727)参考文献

ab56727 has not yet been referenced specifically in any publications.

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