重组狗Prorenin蛋白(ab92555)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE
描述
-
产品名称
重组狗Prorenin蛋白
参阅全部 Prorenin 蛋白酶 -
纯度
> 95 % SDS-PAGE.
Purified by chelated metal affinity chromatography -
表达系统
HEK 293 cells -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Dog
-
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab92555 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
-
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituent: 0.79% Tris HCl
常规信息
-
别名
- Angiotensin forming enzyme
- Angiotensinogenase
- FLJ10761
see all -
功能
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. -
疾病相关
Defects in REN are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
Defects in REN are the cause of familial juvenile hyperuricemic nephropathy type 2 (HNFJ2) [MIM:613092]. It is a renal disease characterized by juvenile onset of hyperuricemia, slowly progressive renal failure and anemia. -
序列相似性
Belongs to the peptidase A1 family. -
细胞定位
Secreted. Membrane. Associated to membranes via binding to ATP6AP2. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (0)
ab92555 尚未被引用在任何文献中。