Recombinant DnaK protein (ab51115)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 序列MDVKDVLLLD VTPLSLGIET MGGVMTTLIA KNTTIPTKHS QVFSTAEDNQ SAVTIHVLQG ERKRAADNKS LGQFNLDGIN PAPRGMPQIE VTFDIDADGI LHVSAKDKNS GKEQKITIKA SSGLNEDEIQ KMVRDAEANA ADRKFEELV QTRNQGDHLL HST
    • 氨基酸385 to 546

技术指标

Our Abpromise guarantee covers the use of ab51115 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    This recombinant protein was purified to apparent homogeneity by using conventional column chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25mM Tris HCl, 2mM Beta mercaptoethanol, 1mM EDTA, pH 7.5

常规信息

  • 别名
    • Chaperone Hsp70
    • Chaperone protein dnaK
    • Co chaperone with DnaJ
    • dnaK
    • Heat shock 70 kDa protein
    • HSP70
    see all
  • 相关性DnaK is the prokaryotic analogue of eukaryotic Hsp70. Heat shock proteins applies to a group of proteins that assist in the assembly, folding, and translocation of other proteins. In addition, they protect the cell against heat injury or other forms of stress. All cells, prokaryotic and eukaryotic, are able to respond to different cellular stresses by synthesizing these proteins. Heat shock proteins are highly conserved, ubiquitously distributed, and involved in important aspects of viral and bacterial infections, autoimmune diseases, and in cancer immunity. Two families of molecular chaperones have been identified. The members of the Hsp70 family (DnaK/DnaJ/GrpE) bind to the growing polypeptide chain and prevent its premature folding. The chaperonin family (GroEL and GroES) assists in correct folding when the complete polypeptide chain is formed and is transported into the cytosol or mitochondria. All the major heat shock proteins help to suppress irreversible unfolding reactions. These protein folding 'assistants' may have important functions in amyloid diseases where incorrectly folded proteins accumulate as folded aggregates.
  • 细胞定位Cytoplasm. Cell inner membrane; Peripheral membrane protein.

Recombinant DnaK protein 图像

  • ab51115 in 15% SDS-PAGE

Recombinant DnaK protein (ab51115)参考文献

ab51115 has not yet been referenced specifically in any publications.

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