Recombinant牛IL23 protein (ab87524)

概述

描述

  • 性质
    Recombinant
  • 来源
    Yeast
  • 氨基酸序列
    • 种属
      Cow
    • 序列
      RAVSEDSSPA WTRGQQLSQQ LCMLAWSAHL PMGHMDLPRE EGGDKTTDDV PRIQCEDGCD PQGLRDNSQS CLQRIHRGLV FYEKLLGSDI FTGEPSLLPN GPVDQLHASI LGLRELLQPK GHHWETEQTP SPIPSQPWQR LLLRLKILRS LQAFVAVAAR VFAHGAATLS P

技术指标

Our Abpromise guarantee covers the use of ab87524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.
    ab87524 is purified by Ion-exchange chromatography.
  • 形式
    Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Preservative: None
    Constituents: 10% Trehalose, 1X PBS

  • 复溶
    Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.

常规信息

  • 别名
    • IL 23
    • IL 23 A
    • IL 23 subunit alpha
    • IL 23A
    • IL 23p19
    • IL-23 subunit alpha
    • IL-23-A
    • IL-23p19
    • IL12B
    • IL23
    • Il23a
    • IL23A_HUMAN
    • IL23P19
    • interleukin 12B
    • Interleukin 23 alpha subunit p19
    • Interleukin 23 p19 subunit
    • interleukin 23 subunit alpha
    • interleukin 23 subunit p19
    • interleukin six, G CSF related factor
    • Interleukin-23 subunit alpha
    • Interleukin-23 subunit p19
    • JKA3 induced upon T cell activation
    • MGC79388
    • P19
    • SGRF
    see all
  • 功能
    Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
  • 组织特异性
    Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level).
  • 序列相似性
    Belongs to the IL-6 superfamily.
  • 发展阶段
    Expressed by newborns dendritic cells.
  • 细胞定位
    Secreted. Secreted upon association with IL12B.
  • Information by UniProt

Recombinant Cow IL23 protein (ab87524)参考文献

ab87524 has not yet been referenced specifically in any publications.

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