This product is an active protein and may elicit a biological response in vivo, handle with caution.
复溶Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
C-X-C motif chemokine 11
Chemokine (C-X-C motif) ligand 11
Chemokine C-X-C motif ligand 11
Interferon gamma inducible protein 9
Interferon gamma-inducible protein 9
Interferon inducible T cell alpha chemoattractant
Interferon-inducible T-cell a chemoattractant I-TAC
Interferon-inducible T-cell alpha chemoattractant
Small inducible cytokine B11
Small inducible cytokine subfamily B (Cys-X-Cys) member 11
Small inducible cytokine subfamily B (Cys-X-Cys) member 9B
Small inducible cytokine subfamily B, member 11
Small inducible cytokine subfamily B, member 9B
Small-inducible cytokine B11
功能Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
组织特异性High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.
序列相似性Belongs to the intercrine alpha (chemokine CxC) family.