Recombinant Asparaginase protein (ab73439)

概述

  • 产品名称Recombinant Asparaginase protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli

技术指标

Our Abpromise guarantee covers the use of ab73439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性

    Specific activity is 225 IU/mg. One IU of L- Asparaginase is defined as that amount of enzyme required to generate 1 µmol of ammonia per minute at pH 7.3 and 37°C.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Purity is greater than 96.0% as determined by RP-HPLC and SDS-PAGE.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    No additives

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶It is recommended to reconstitute the lyophilized Asparaginase in 18M-cm H2O at 1mg/ml.

常规信息

  • 别名
    • AnsA
    • AnsB
    • Colaspase
    • Cytoplasmic asparaginase I
    • L ASNase I
    • L ASNase II
    • L asparaginase 1
    • L asparaginase 2
    • L asparaginase I
    • L asparaginase II
    • L asparaginase II precursor
    • L asparagine amidohydrolase I
    • L asparagine amidohydrolase II
    see all
  • 相关性Asparaginase is an enzyme purified from E. coli and Erwinia carotovora. It acts by deaminating extracellular L asparagine, an amino acid that appears to be essential for protein synthesis by some tumour cells which are unable to synthesise asparagine. Asparaginase from Erwinia carotovora is serologically and biochemically distinct from asparaginase from E. coli, although its antineoplastic activity and toxicity is similar. Asparaginase is usually considered to be cell cycle phase nonspecific, but it may block some cells in G1 or S phase. Asparaginase reduces cellular and humoral immunity. E.coli contains two L asparaginase isoenzymes: L asparaginase I, a low affinity enzyme located in the cytoplasm, and L asparaginase II, a high affinity secreted enzyme.
  • 细胞定位Cytoplasmic, Secreted and Periplasm.

Recombinant Asparaginase protein (ab73439)参考文献

ab73439 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"