Recombinant Agitoxin2 protein (ab57372)

概述

  • 产品名称Recombinant Agitoxin2 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli

技术指标

Our Abpromise guarantee covers the use of ab57372 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Preservative: None
    Constituents: 0.1% BSA, 100mM Sodium chloride, 10mM Tris, 1mM EDTA, pH 7.5

  • 复溶Reconstitute with 10 mM Tris, pH 7.5, containing 100 mM sodium chloride, 0.1% bovine serum albumin and 1 mM EDTA.

常规信息

  • 别名
    • Agitoxin 2
    • AgTx 2
    • AgTx2
    • Potassium channel toxin alpha KTx 3.2
  • 相关性Agitoxin is a toxin found in the venom of the scorpion Leiurus quinquestriatus herbraeus (yellow scorpion). Agitoxin binds to the Shaker K+ channel in Drosophila as well as to its mammalian homologue. It blocks this channel by binding with high affinity (Kd < 1 nM) to its external vestibule. Its structure consists of a triple-stranded antiparallel beta-sheet and a single helix covering one face of the beta-sheet. The cysteine side chains connect the beta-sheet and the helix form to the core of the molecule. The fold of agitoxin is homologous to the previously determined folds of scorpion venom toxins. Three types of agitoxin can be distinguished; all 3 agitoxins have been identified as 38 amino acid toxins (cystine bonds not shown): Agitoxin-2 Gly-Val-Pro-Ile-Asn-Val-Ser-Cys-Thr-Gly-Ser-Pro-Gln-Cys-Ile-Lys-Pro-Cys-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys-Met-Asn-Arg-Lys-Cys-His-Cys-Thr-Pro-Lys Molecular Formula = 169H278N54O48S8
  • 细胞定位Secreted

Recombinant Agitoxin2 protein (ab57372)参考文献

ab57372 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab57372.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"