概述

  • 产品名称Anti-RECK抗体
    参阅全部 RECK 一抗
  • 描述
    小鼠多克隆抗体to RECK
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    RECK full-length human protein (NP_066934.1).

  • 阳性对照
    • RECK transfected 293T cell line and RECK expression in 293 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab88249 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 106 kDa.

靶标

  • 功能Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
  • 组织特异性Expressed in various tissues and untransformed cells. It is undetectable in tumor-derived cell lines and oncogenically transformed cells.
  • 序列相似性Contains 3 Kazal-like domains.
  • 翻译后修饰N-glycosylated.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • hRECK antibody
    • Membrane anchored glycoprotein (metastasis and invasion) antibody
    • RECK antibody
    • RECK protein antibody
    • RECK_HUMAN antibody
    • Reversion inducing cysteine rich protein with Kazal motifs antibody
    • Reversion-inducing cysteine-rich protein with Kazal motifs antibody
    • ST15 antibody
    • Suppression of tumorigenicity 15 (reversion inducing cysteine rich protein with kazal motifs) antibody
    • Suppressor of tumorigenicity 15 antibody
    • Suppressor of tumorigenicity 15 protein antibody
    see all

Anti-RECK antibody 图像

  • Anti-RECK antibody (ab88249) at 1 µg/ml + 293 cell lysate at 50 µg

    Predicted band size : 106 kDa
  • All lanes : Anti-RECK antibody (ab88249) at 1 µg/ml

    Lane 1 : RECK transfected 293T cell line
    Lane 2 : Non-transfected 293T cell line

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 106 kDa
    Observed band size : 106 kDa

Anti-RECK antibody (ab88249)参考文献

This product has been referenced in:
  • Liu W  et al. miR-221 and miR-222 Simultaneously Target RECK and Regulate Growth and Invasion of Gastric Cancer Cells. Med Sci Monit 21:2718-25 (2015). WB ; Human . Read more (PubMed: 26364844) »

See 1 Publication for this product

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