概述

  • 产品名称Anti-REA抗体
    参阅全部 REA 一抗
  • 描述
    兔多克隆抗体to REA
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Cow
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 45-298 of Human REA (NP_009204)

  • 阳性对照
    • H1299 and HeLa whole cell lysates; A431 cells; 293T, HepG2, Molt-4 and Raji cell lines

性能

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应用

Our Abpromise guarantee covers the use of ab97538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
  • 序列相似性Belongs to the prohibitin family.
  • 发展阶段Levels of expression in fibroblasts decrease heterogeneously during cellular aging.
  • 细胞定位Mitochondrion inner membrane. Cytoplasm. Nucleus. Also cytoplasmic and nuclear.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B cell receptor associated protein BAP37 antibody
    • B-cell receptor-associated protein BAP37 antibody
    • BAP antibody
    • Bap37 antibody
    • BCAP 37 antibody
    • D prohibitin antibody
    • D-prohibitin antibody
    • p22 antibody
    • Phb2 antibody
    • PHB2_HUMAN antibody
    • PNAS 141 antibody
    • Prohibitin 2 antibody
    • Prohibitin-2 antibody
    • Repressor of estrogen receptor activity antibody
    see all

Anti-REA antibody 图像

  • All lanes : Anti-REA antibody (ab97538) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 33 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed A431, using ab97538 at 1/200 dilution (1) and merged with DNA probe (2).

Anti-REA antibody (ab97538)参考文献

ab97538 has not yet been referenced specifically in any publications.

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