概述

  • 产品名称Anti-REA抗体
    参阅全部 REA 一抗
  • 描述
    兔多克隆抗体to REA
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rabbit, Guinea pig, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residues 1 and 50 of Human REA (NP_009204.1)

  • 阳性对照
    • Human breast Carcinoma, Human Ovarian Carcinoma or Human Stomach Adenocarcinoma tissue.
  • 常规说明

    Shelf Life: 1 year from date of receipt

    The Alexa Fluor® 488 variant is available.

性能

应用

Our Abpromise guarantee covers the use of ab82547 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining and is recommended


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
    • 序列相似性Belongs to the prohibitin family.
    • 发展阶段Levels of expression in fibroblasts decrease heterogeneously during cellular aging.
    • 细胞定位Mitochondrion inner membrane. Cytoplasm. Nucleus. Also cytoplasmic and nuclear.
    • Information by UniProt
    • 数据库链接
    • 别名
      • B cell receptor associated protein BAP37 antibody
      • B-cell receptor-associated protein BAP37 antibody
      • BAP antibody
      • Bap37 antibody
      • BCAP 37 antibody
      • D prohibitin antibody
      • D-prohibitin antibody
      • p22 antibody
      • Phb2 antibody
      • PHB2_HUMAN antibody
      • PNAS 141 antibody
      • Prohibitin 2 antibody
      • Prohibitin-2 antibody
      • Repressor of estrogen receptor activity antibody
      see all

    Anti-REA antibody 图像

    • ab82547, at a 1:250 dilution, staining Human REA in breast adenocarcinoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue.
    • ab82547, at 1:250 dilution, staining human REA in ovarian carcinoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue.

    Anti-REA antibody (ab82547)参考文献

    ab82547 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"