概述

  • 产品名称Anti-RDH11抗体
    参阅全部 RDH11 一抗
  • 描述
    兔多克隆抗体to RDH11
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptides to N terminal sequence MVELMFP (amino acids 1-7) and the C terminal sequence LLGLPID (amino acids 312-318) of Human RDH11

  • 阳性对照
    • Human kidney tissue

性能

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应用

Our Abpromise guarantee covers the use of ab85849 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 35 kDa.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected.
  • 组织特异性Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes.
  • 序列相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 翻译后修饰Not glycosylated.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Androgen regulated short chain dehydrogenase/reductase 1 antibody
    • Androgen-regulated short-chain dehydrogenase/reductase 1 antibody
    • ARSDR1 antibody
    • AU045252 antibody
    • C85936 antibody
    • CGI 82 antibody
    • FLJ32633 antibody
    • HCBP12 antibody
    • HCV core binding protein antibody
    • HCV core binding protein HCBP12 antibody
    • HCV core-binding protein HCBP12 antibody
    • MDT1 antibody
    • Prostate short chain dehydrogenase/reductase 1 antibody
    • Prostate short-chain dehydrogenase/reductase 1 antibody
    • PSDR1 antibody
    • RALR1 antibody
    • RDH11 antibody
    • RDH11_HUMAN antibody
    • Retinal reductase 1 antibody
    • retinol dehydrogenase 11 (all trans/9 cis/11 cis) antibody
    • Retinol dehydrogenase 11 antibody
    • SCALD antibody
    • SDR7C1 antibody
    • Short chain dehydrogenase/reductase family 7C, member 1 antibody
    see all

Anti-RDH11 antibody 图像

  • Formalin fixed and paraffin embedded human kidney tissue labelled with ab85849 at 5 µg/ml.

Anti-RDH11 antibody (ab85849)参考文献

ab85849 has not yet been referenced specifically in any publications.

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