概述

  • 产品名称Anti-RC3H1抗体
    参阅全部 RC3H1 一抗
  • 描述
    兔多克隆抗体to RC3H1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 1014-1043 of Human RC3H1 (NP_742068.1).

  • 阳性对照
    • NCI-H460 cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab116291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 126 kDa.

靶标

  • 功能Represses ICOS function, an essential costimulatory receptor for follicular T-cells. May act as an ubiquitin ligase that regulates ubiquitin-dependent control of AU-rich mRNAs by AUF1/HNRPD and HUR/ELAVL1.
  • 组织特异性Widely expressed. Expressed at higher level in cerebellum, spleen, ovary and liver.
  • 序列相似性Contains 1 C3H1-type zinc finger.
    Contains 1 RING-type zinc finger.
  • 细胞定位Cytoplasm. Localizes to cytosolic RNA granules, which are sites for regulating mRNA translation and decay, suggesting that it may bind RNA.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA2025 antibody
    • Rc3h1 antibody
    • RC3H1_HUMAN antibody
    • RGD1563512 antibody
    • RING finger and C3H zinc finger protein 1 antibody
    • Ring Finger and CCCH type Zinc Finger Domain 1 antibody
    • RING finger protein 198 antibody
    • RNF198 antibody
    • Roquin antibody
    • RP5 1198E17.5 antibody
    • Sanroque protein antibody
    see all

Anti-RC3H1 antibody 图像

  • Anti-RC3H1 antibody (ab116291) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

    Predicted band size : 126 kDa

Anti-RC3H1 antibody (ab116291)参考文献

ab116291 has not yet been referenced specifically in any publications.

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