产品名称 Anti-RC3H1抗体 参阅全部 RC3H1 一抗
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Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 1014-1043 of Human RC3H1 (NP_742068.1).
NCI-H460 cell line lysates.
存放说明 Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
存储溶液 Preservative: 0.09% Sodium azide Constituent: 99% PBS
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纯度 Immunogen affinity purified
纯化说明 ab116291 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 126 kDa.
功能 Represses ICOS function, an essential costimulatory receptor for follicular T-cells. May act as an ubiquitin ligase that regulates ubiquitin-dependent control of AU-rich mRNAs by AUF1/HNRPD and HUR/ELAVL1.
组织特异性 Widely expressed. Expressed at higher level in cerebellum, spleen, ovary and liver.
序列相似性 Contains 1 C3H1-type zinc finger. Contains 1 RING-type zinc finger.
细胞定位 Cytoplasm. Localizes to cytosolic RNA granules, which are sites for regulating mRNA translation and decay, suggesting that it may bind RNA.
Information by UniProt
Anti-RC3H1 antibody (ab116291)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"