Anti-RBPJK抗体[RPBS3D18] (ab51371)

概述

  • 产品名称Anti-RBPJK抗体[RPBS3D18]
    参阅全部 RBPJK 一抗
  • 描述
    小鼠单克隆抗体[RPBS3D18] to RBPJK
  • 特异性The antibody has not yet been tested on endogenous protein or cell lysate.
  • 经测试应用适用于: Dot blot, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment (Human)

性能

应用

Our Abpromise guarantee covers the use of ab51371 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Dot blot Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 56 kDa.

靶标

  • 功能Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
  • 序列相似性Belongs to the Su(H) family.
    Contains 1 IPT/TIG domain.
  • 细胞定位Nucleus. Cytoplasm. Mainly nuclear, upon interaction with RITA/C12orf52, translocates to the cytoplasm, down-regulating the Notch signaling pathway.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI843960 antibody
    • CBF 1 antibody
    • CBF-1 antibody
    • CBF1 antibody
    • IGKJRB1 antibody
    • J kappa recombination signal binding protein antibody
    • J kappa-recombination signal-binding protein antibody
    • KBF2 antibody
    • NY REN 30 antigen antibody
    • RBP J kappa antibody
    • RBP-J antibody
    • RBP-J kappa antibody
    • RBP-JK antibody
    • Rbpj antibody
    • RBPJK antibody
    • RBPSUH antibody
    • Recombining binding protein suppressor of hairless antibody
    • Renal carcinoma antigen NY-REN-30 antibody
    • SUH_HUMAN antibody
    see all

Anti-RBPJK antibody [RPBS3D18] 图像

  • Lane 1 : Molecular weight markers
    Lane 2 : Anti-RBPJK antibody [RPBS3D18] (ab51371)

    Lane 1 : As above
    Lane 2 : immunizing peptide


    Predicted band size : 56 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-RBPJK antibody [RPBS3D18] (ab51371)参考文献

ab51371 has not yet been referenced specifically in any publications.

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