概述

  • 产品名称Anti-RBPJK抗体
    参阅全部 RBPJK 一抗
  • 描述
    小鼠单克隆抗体to RBPJK
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 3-110 of Human RBPJK

性能

应用

Our Abpromise guarantee covers the use of ab55366 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
    • 序列相似性Belongs to the Su(H) family.
      Contains 1 IPT/TIG domain.
    • 细胞定位Nucleus. Cytoplasm. Mainly nuclear, upon interaction with RITA/C12orf52, translocates to the cytoplasm, down-regulating the Notch signaling pathway.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AI843960 antibody
      • CBF 1 antibody
      • CBF-1 antibody
      • CBF1 antibody
      • IGKJRB1 antibody
      • J kappa recombination signal binding protein antibody
      • J kappa-recombination signal-binding protein antibody
      • KBF2 antibody
      • NY REN 30 antigen antibody
      • RBP J kappa antibody
      • RBP-J antibody
      • RBP-J kappa antibody
      • RBP-JK antibody
      • Rbpj antibody
      • RBPJK antibody
      • RBPSUH antibody
      • Recombining binding protein suppressor of hairless antibody
      • Renal carcinoma antigen NY-REN-30 antibody
      • SUH_HUMAN antibody
      see all

    Anti-RBPJK antibody 图像



    • Predicted band size : 56 kDa

    Anti-RBPJK antibody (ab55366)参考文献

    ab55366 has not yet been referenced specifically in any publications.

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