Anti-Rbm15/OTT抗体(ab96544)
Key features and details
- Rabbit polyclonal to Rbm15/OTT
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-Rbm15/OTT抗体
参阅全部 Rbm15/OTT 一抗 -
描述
兔多克隆抗体to Rbm15/OTT -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
Recombinant fragment corresponding to Human Rbm15/OTT aa 146-395.
Database link: NP_073605 -
阳性对照
- WB: A431, H1299 and Hela cell lystes IHC-P: HeLa cells
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96544于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 107 kDa.
|
|
ICC/IF |
1/100 - 1/200.
|
说明 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 107 kDa. |
ICC/IF
1/100 - 1/200. |
靶标
-
功能
May be implicated in HOX gene regulation. -
疾病相关
A chromosomal aberration involving RBM15 may be a cause of acute megakaryoblastic leukemia. Translocation t(1;22)(p13;q13) with MKL1. Although both reciprocal fusion transcripts are detected in acute megakaryoblastic leukemia (AMKL, FAB-M7), the RBM15-MKL1 chimeric protein has all the putative functional domains encoded by each gene and is the candidate oncogene. -
序列相似性
Belongs to the RRM Spen family.
Contains 3 RRM (RNA recognition motif) domains.
Contains 1 SPOC domain. -
细胞定位
Nucleus. - Information by UniProt
-
数据库链接
- Entrez Gene: 64783 Human
- Entrez Gene: 229700 Mouse
- Omim: 606077 Human
- SwissProt: Q96T37 Human
- SwissProt: Q6PHZ5 Mouse
- Unigene: 435947 Human
- Unigene: 708172 Human
-
别名
- One twenty two protein antibody
- One-twenty two protein 1 antibody
- OTT antibody
see all
图片
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (2)
ab96544 被引用在 2 文献中.
- Ma M et al. The prognostic value of N6-methyladenosine RBM15 regulators in lung adenocarcinoma. Cell Mol Biol (Noisy-le-grand) 68:130-139 (2022). PubMed: 35809319
- Elman JS et al. Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing. Cell Rep 28:3435-3449.e5 (2019). PubMed: 31553912