概述

  • 产品名称Anti-RbBP5抗体
    参阅全部 RbBP5 一抗
  • 描述
    兔多克隆抗体to RbBP5
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Horse, Cow, Rhesus monkey, Gorilla, Orangutan, Bat, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residues 500 and the C-terminus (residue 538) of Human RbBP5 (NP_005048.2).

  • 阳性对照
    • Human colon adenocarcinoma and mouse teratoma tissues.

性能

应用

Our Abpromise guarantee covers the use of ab84511 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
    • 组织特异性Ubiquitously expressed.
    • 序列相似性Contains 6 WD repeats.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • RBBP 5 antibody
      • RBBP-5 antibody
      • RBBP5 antibody
      • RBBP5_HUMAN antibody
      • RBQ 3 antibody
      • RBQ3 antibody
      • Retinoblastoma binding protein 5 antibody
      • Retinoblastoma binding protein RBQ3 antibody
      • Retinoblastoma binding protein5 antibody
      • Retinoblastoma-binding protein 5 antibody
      • Retinoblastoma-binding protein RBQ-3 antibody
      • SWD1 antibody
      • SWD1, Set1c WD40 repeat protein, homolog antibody
      see all

    Anti-RbBP5 antibody 图像

    • ab84511, at 1/250 dilution, staining RbBP5 in formalin-fixed, paraffin-embedded human colon adenocarcinoma by Immunohistochemistry, using DAB staining.
    • ab84511, at 1/250 dilution, staining RbBP5 in formalin-fixed, paraffin-embedded mouse teratoma by Immunohistochemistry, using DAB staining.

    Anti-RbBP5 antibody (ab84511)参考文献

    This product has been referenced in:
    • Yan L  et al. The B55a-containing PP2A holoenzyme dephosphorylates FOXO1 in islet ß-cells under oxidative stress. Biochem J 444:239-47 (2012). IHC-P ; Mouse . Read more (PubMed: 22417654) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab84511.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"