概述

  • 产品名称Anti-Rb2 p130抗体
    参阅全部 Rb2 p130 一抗
  • 描述
    兔多克隆抗体to Rb2 p130
  • 特异性ab105741 reacts with the Spa3120 domain of pRb2 p130 from Human tissues.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Horse, Cow, Dog, Chimpanzee, Opossum, Orangutan
  • 免疫原

    Synthetic peptide with a Cysteine residue linker, corresponding to the Spa310 sequence of Rb2 p130.

  • 阳性对照
    • LNCaP whole cell extracts.

性能

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应用

Our Abpromise guarantee covers the use of ab105741 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/5000. Predicted molecular weight: 128 kDa.
ELISA 1/75000 - 1/100000.

靶标

  • 相关性Two retinoblastoma related proteins, p107 and pRb2 / p130, which are structurally and functionally similar to the product of the retinoblastoma gene (pRb / p105), were cloned by taking advantage of their ability to bind transforming proteins of DNA tumor viruses through a particular region called the "pocket domain." Like pRb, both proteins play a fundamental role in growth control. These Rb family proteins were measured in a variety of lung neoplasms. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2 / p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • 130 kDa retinoblastoma associated protein antibody
    • FLJ26459 antibody
    • p130 antibody
    • PRB 2 antibody
    • PRB2 antibody
    • Rb 2 antibody
    • Rb2 antibody
    • RBL 2 antibody
    • RBL2 antibody
    • RBR 2 antibody
    • RBR2 antibody
    • Retinoblastoma like 2 antibody
    • Retinoblastoma like protein 2 antibody
    • Retinoblastoma related gene antibody
    see all

Anti-Rb2 p130 antibody 图像

  • Anti-Rb2 p130 antibody (ab105741) at 1/500 dilution + LNCaP whole cell extracts
    Developed using the ECL technique

    Predicted band size : 128 kDa

Anti-Rb2 p130 antibody (ab105741)参考文献

ab105741 has not yet been referenced specifically in any publications.

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