Anti-RAX抗体(ab23340)

概述

  • 产品名称Anti-RAX抗体
    参阅全部 RAX 一抗
  • 描述
    兔多克隆抗体to RAX
  • 特异性ab23340 reacts with RAX (retinal homeobox protein Rx).
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide corresponding to Human RAX aa 1-50.
    Sequence:

    MHLPGCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKDDGILGT


    Database link: Q9Y2V3

  • 阳性对照
    • Jurkat cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab23340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
WB Use a concentration of 0.2 - 5 µg/ml. Detects a band of approximately 32 kDa (predicted molecular weight: 38 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
  • 组织特异性Expressed in the developing eye and weakly expressed in the adult retina.
  • 疾病相关Defects in RAX are the cause of microphthalmia isolated type 3 (MCOP3) [MIM:611038]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present.
  • 序列相似性Belongs to the paired homeobox family. Bicoid subfamily.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MCOP3 antibody
    • RAX antibody
    • retina and anterior neural fold homeobox antibody
    • Retina and anterior neural fold homeobox protein antibody
    • Retinal homeobox protein Rx antibody
    • RX antibody
    • RX_HUMAN antibody
    see all

Anti-RAX antibody 图像

  • Anti-RAX antibody (ab23340) at 1 µg/ml + Jurkat cell lysate

    Performed under reducing conditions.

    Predicted band size : 38 kDa
    Observed band size : 32 kDa (why is the actual band size different from the predicted?)
  • ab23340 at 4.0 µg/ml staining human spermatophore by IHC-P.  Epithelial cells, with positive label, are indicated with arrows. Magnification 400X.

Anti-RAX antibody (ab23340)参考文献

ab23340 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry and for your patience. It has taken some time to discuss this with our source for this antibody.

It is unfortunately difficult to say what the lighter brown staining is exactly in the IHC image provided for ab23340...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"