概述

  • 产品名称
    大鼠LMAN1肽

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Rat
    • 序列
      FDSFDNDGKKNNPAI
    • 氨基酸
      159 to 173

相关产品

技术指标

Our Abpromise guarantee covers the use of ab39824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-LMAN1 antibody (ab32583)

    Neutralising

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • Endoplasmic reticulum golgi intermediate compartment protein 53
    • ER-Golgi intermediate compartment 53 kDa protein
    • ERGIC-53
    • ERGIC53
    • ERGIC53 like protein
    • F5F8D
    • FMFD1
    • Gp58
    • Intracellular mannose specific lectin
    • Intracellular mannose-specific lectin MR60
    • Lectin mannose binding 1
    • Lectin mannose-binding 1
    • Lman1
    • LMAN1 like protein
    • LMAN1_HUMAN
    • MCFD1
    • MR60
    • Protein ERGIC-53
    see all
  • 功能
    Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
  • 组织特异性
    Ubiquitous.
  • 疾病相关
    Defects in LMAN1 are THE cause of factor V and factor VIII combined deficiency type 1 (F5F8D1) [MIM:227300]; also known as multiple coagulation factor deficiency I (MCFD1). F5F8D1 is an autosomal recessive blood coagulation disorder characterized by bleeding symptoms similar to those in hemophilia or parahemophilia, that are caused by single deficiency of FV or FVIII, respectively. The most common symptoms are epistaxis, menorrhagia, and excessive bleeding during or after trauma. Plasma levels of coagulation factors V and VIII are in the range of 5 to 30% of normal.
  • 序列相似性
    Contains 1 L-type lectin-like domain.
  • 翻译后修饰
    The N-terminal may be partly blocked.
  • 细胞定位
    Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus membrane. Endoplasmic reticulum membrane.
  • Information by UniProt

文献

ab39824 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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